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Hae Young Chung Selected Research

N1- hydroxy- N8- (4- phenoxyphenyl)octanediamide

8/2015MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells.
1/2014A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-κB in HCT116 human colon cancer cells.
10/2012A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells.

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Hae Young Chung Research Topics

Disease

65Inflammation (Inflammations)
10/2022 - 04/2002
37Neoplasms (Cancer)
10/2021 - 02/2003
24Melanoma (Melanoma, Malignant)
05/2022 - 02/2005
17Insulin Resistance
01/2021 - 01/2013
14Body Weight (Weight, Body)
05/2021 - 04/2002
13Colonic Neoplasms (Colon Cancer)
09/2019 - 07/2004
9Hyperpigmentation
12/2018 - 04/2011
8Fibrosis (Cirrhosis)
03/2022 - 05/2013
7Carcinogenesis
07/2022 - 06/2002
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020 - 02/2004
6Alzheimer Disease (Alzheimer's Disease)
09/2016 - 02/2004
5Colorectal Neoplasms (Colorectal Cancer)
07/2022 - 03/2014
5Parkinson Disease (Parkinson's Disease)
01/2022 - 01/2017
5Type 2 Diabetes Mellitus (MODY)
01/2021 - 01/2013
5Hypoxia (Hypoxemia)
08/2017 - 11/2002
5Breast Neoplasms (Breast Cancer)
08/2017 - 09/2007
5Chronic Disease (Chronic Diseases)
02/2015 - 06/2007
4Colitis
01/2022 - 09/2014
4Stomach Neoplasms (Stomach Cancer)
12/2018 - 06/2013
4Obesity
08/2018 - 10/2010
4Pigmentation Disorders (Ito Syndrome)
04/2015 - 01/2004
4Experimental Melanoma
10/2013 - 02/2006
4Atherosclerosis
12/2008 - 09/2005
3Neuroinflammatory Diseases
11/2021 - 01/2019
3Hyperinsulinism (Hyperinsulinemia)
10/2021 - 12/2014
3Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 10/2008
3Neuroblastoma
01/2019 - 01/2008
3Melanosis (Freckles)
12/2018 - 10/2013
3Fatty Liver
01/2018 - 08/2015
3Cardiovascular Diseases (Cardiovascular Disease)
10/2015 - 09/2004
3Prostatic Neoplasms (Prostate Cancer)
03/2014 - 05/2011
3Hepatocellular Carcinoma (Hepatoma)
05/2012 - 02/2003
2Hyperlipidemias (Hyperlipidemia)
01/2021 - 12/2008
2Congenital Abnormalities (Deformity)
07/2019 - 10/2015
2Non-alcoholic Fatty Liver Disease
08/2018 - 01/2018
2Weight Gain
08/2018 - 01/2017
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2018 - 06/2010
2Lung Neoplasms (Lung Cancer)
01/2018 - 11/2015

Drug/Important Bio-Agent (IBA)

26Monophenol Monooxygenase (Tyrosinase)IBA
05/2022 - 02/2005
25Melanins (Melanin)IBA
05/2022 - 01/2004
19LipidsIBA
10/2021 - 06/2002
17Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2002
15Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2021 - 10/2004
15Transcription Factors (Transcription Factor)IBA
11/2020 - 10/2004
14NF-kappa B (NF-kB)IBA
10/2017 - 11/2002
12Melanocyte-Stimulating Hormones (MSH)IBA
12/2018 - 04/2012
10AntioxidantsIBA
10/2021 - 02/2004
8Glucose (Dextrose)FDA LinkGeneric
11/2020 - 09/2002
7CytokinesIBA
07/2022 - 01/2007
7Insulin (Novolin)FDA Link
11/2020 - 01/2013
6Therapeutic UsesIBA
01/2022 - 05/2012
6Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2019 - 10/2004
6ResveratrolIBA
01/2018 - 12/2013
5Sirtuin 1IBA
07/2022 - 01/2018
5FlavonoidsIBA
05/2014 - 09/2002
4CaspasesIBA
01/2022 - 02/2006
4Biological ProductsIBA
11/2021 - 09/2006
4Reactive Oxygen Species (Oxygen Radicals)IBA
10/2021 - 02/2004
4AcidsIBA
01/2020 - 01/2013
4InflammasomesIBA
08/2018 - 08/2015
44-(6-hydroxy-2-naphthyl)-1,3-benzenediolIBA
08/2017 - 12/2013
4Antineoplastic Agents (Antineoplastics)IBA
08/2017 - 01/2010
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2017 - 01/2013
4Betaine (C.B.B.)FDA Link
01/2017 - 10/2005
4MHY-449IBA
11/2015 - 12/2012
3SirtuinsIBA
07/2022 - 11/2020
3ChemokinesIBA
03/2022 - 01/2006
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2022 - 02/2004
3Phosphotransferases (Kinase)IBA
01/2022 - 01/2018
3Peptides (Polypeptides)IBA
01/2022 - 02/2004
31- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
11/2021 - 01/2019
3Pharmaceutical PreparationsIBA
09/2019 - 06/2011
3Neuroprotective AgentsIBA
01/2019 - 09/2016
31-Methyl-3-isobutylxanthine (1 Methyl 3 isobutylxanthine)IBA
12/2018 - 03/2018
3Fatty Acids (Saturated Fatty Acids)IBA
01/2018 - 07/2017
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2017 - 01/2010
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
05/2017 - 01/2013
3Indicators and Reagents (Reagents)IBA
01/2017 - 09/2002
3ApigeninIBA
12/2016 - 02/2003
3N1- hydroxy- N8- (4- phenoxyphenyl)octanediamideIBA
08/2015 - 10/2012
3Peroxynitrous Acid (Peroxynitrite)IBA
03/2014 - 06/2002
3baicalinIBA
01/2013 - 09/2006
3Histone Deacetylase InhibitorsIBA
12/2012 - 01/2010
3Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2006 - 09/2005
2AdenineFDA LinkGeneric
03/2022 - 11/2021
2Peptide Hydrolases (Proteases)FDA Link
03/2022 - 01/2021
2barbituric acid (barbiturate)IBA
11/2021 - 10/2017
2Folic Acid (Vitamin M)FDA LinkGeneric
11/2021 - 10/2015
2VaccinesIBA
08/2021 - 04/2008
2MHY3200IBA
05/2021 - 08/2018
2PAR-2 ReceptorIBA
01/2021 - 01/2021
2hemoglobin ASIBA
01/2019 - 05/2003
2Microphthalmia-Associated Transcription FactorIBA
11/2018 - 04/2012
2lithospermate BIBA
08/2018 - 05/2017
2Triglycerides (Triacylglycerol)IBA
01/2018 - 01/2013
2EnzymesIBA
01/2018 - 03/2016
2LigandsIBA
10/2017 - 04/2012

Therapy/Procedure

11Therapeutics
08/2021 - 06/2006
6Chemoprevention
11/2020 - 01/2014
4Oral Administration
08/2014 - 09/2002